Phenotypes associated with this allele

• Allele Symbol: Odaph^tm1Cya
• Allele Name: targeted mutation 1, Cyagen Biosciences
• Allele ID: MGI:6781218
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Odaph^tm1Cya/Odaph^tm1Cya	Not Specified	MGI:6781219

Genotype
MGI:6781219

hm1

• Allelic Composition: Odaph^tm1Cya/Odaph^tm1Cya
• Genetic Background: Not Specified

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

craniofacial

abnormal ameloblast morphology ( J:311836 )

• during the early maturation stage, ameloblasts become a mass of disorganized flattened epithelial cells with cyst-like structures and defective atypical basal lamina unlike in wild-type mice

abnormal enamel mineralization ( J:311836 )

• impaired

abnormal enamel rod pattern ( J:311836 )

• loosely packed rods and loss of enamel rods

delaminated enamel ( J:311836 )

• at 1 month of age, mice exhibit severely chipped enamel layer of upper and lower incisors, and molars with labial enamel near the gingiva a chalky-white-color unlike wild-type mice

abnormal mandible morphology ( J:311836 )

• transient radiolucent lesion during tooth development

growth/size/body

abnormal ameloblast morphology ( J:311836 )

• during the early maturation stage, ameloblasts become a mass of disorganized flattened epithelial cells with cyst-like structures and defective atypical basal lamina unlike in wild-type mice

abnormal enamel mineralization ( J:311836 )

• impaired

abnormal enamel rod pattern ( J:311836 )

• loosely packed rods and loss of enamel rods

delaminated enamel ( J:311836 )

• at 1 month of age, mice exhibit severely chipped enamel layer of upper and lower incisors, and molars with labial enamel near the gingiva a chalky-white-color unlike wild-type mice

skeleton

abnormal ameloblast morphology ( J:311836 )

• during the early maturation stage, ameloblasts become a mass of disorganized flattened epithelial cells with cyst-like structures and defective atypical basal lamina unlike in wild-type mice

abnormal enamel mineralization ( J:311836 )

• impaired

abnormal enamel rod pattern ( J:311836 )

• loosely packed rods and loss of enamel rods

delaminated enamel ( J:311836 )

• at 1 month of age, mice exhibit severely chipped enamel layer of upper and lower incisors, and molars with labial enamel near the gingiva a chalky-white-color unlike wild-type mice

abnormal mandible morphology ( J:311836 )

• transient radiolucent lesion during tooth development