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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Srsf7em1Mmri
endonuclease-mediated mutation 1, Masaki Mori
MGI:6781649
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Srsf7em1Mmri/Srsf7em1Mmri involves: C57BL/6N MGI:6781650
ht2
 		Srsf7em1Mmri/Srsf7+ involves: C57BL/6N MGI:6781651


Genotype
MGI:6781650
hm1
Allelic
Composition		 Srsf7em1Mmri/Srsf7em1Mmri
Genetic
Background		 involves: C57BL/6N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Srsf7em1Mmri mutation (0 available); any Srsf7 mutation (16 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
embryonic lethality prior to organogenesis, complete penetrance ( J:311518 )
• no homozygous embryos are found at E7.5
• in vitro, embryos are able to reach the blastocyst stage suggesting lethality after the blastocyst stage




Genotype
MGI:6781651
ht2
Allelic
Composition		 Srsf7em1Mmri/Srsf7+
Genetic
Background		 involves: C57BL/6N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Srsf7em1Mmri mutation (0 available); any Srsf7 mutation (16 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
growth/size/body
decreased body weight ( J:311518 )
• in both males and females
slow postnatal weight gain ( J:311518 )
• in both males and females




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory