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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Hint1tm1b(EUCOMM)Wtsi
targeted mutation 1b, Wellcome Trust Sanger Institute
MGI:6782387
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
ht1
 		Hint1tm1b(EUCOMM)Wtsi/Hint1+ C57BL/6N-Hint1tm1b(EUCOMM)Wtsi MGI:6782392


Genotype
MGI:6782392
ht1
Allelic
Composition		 Hint1tm1b(EUCOMM)Wtsi/Hint1+
Genetic
Background		 C57BL/6N-Hint1tm1b(EUCOMM)Wtsi
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Hint1tm1b(EUCOMM)Wtsi mutation (0 available); any Hint1 mutation (25 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
cardiovascular system
decreased response of heart to induced stress ( J:311513 )
• following transverse aorta constriction mice display reduced fractional shortening, ventricular dilation, and cardiomyocyte enlargement compared to similarly treated wild-type controls

homeostasis/metabolism
decreased response of heart to induced stress ( J:311513 )
• following transverse aorta constriction mice display reduced fractional shortening, ventricular dilation, and cardiomyocyte enlargement compared to similarly treated wild-type controls




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory