All Phenotypes Irgm2<em2Myam> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Irgm2^em2Myam
endonuclease-mediated mutation 2, Masahiro Yamamoto
MGI:6784012

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
cx1	Igtp^em1Myam/Igtp^em1Myam Irgm1^em1Myam/Irgm1^em1Myam Irgm2^em2Myam/Irgm2^em2Myam	C57BL/6-Irgm1^em1Myam Igtp^em1Myam Irgm2^em2Myam	MGI:6790418

Allelic Composition	Igtp^em1Myam/Igtp^em1Myam Irgm1^em1Myam/Irgm1^em1Myam Irgm2^em2Myam/Irgm2^em2Myam
Genetic Background	C57BL/6-Irgm1^em1Myam Igtp^em1Myam Irgm2^em2Myam

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Igtp^em1Myam mutation (0 available); any Igtp mutation (22 available)
Irgm1^em1Myam mutation (0 available); any Irgm1 mutation (26 available)
Irgm2^em2Myam mutation (0 available); any Irgm2 mutation (26 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

immune system

increased susceptibility to parasitic infection ( J:308470 )

• bone marrow-derived macrophages, bone marrow-derived dendritic cells, and mouse embryonic fibroblast exhibit impaired IFN-gamma-induced reduction of T. gondii numbers compared with wild-type cells

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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