All Phenotypes Mfrp<rd6-2J> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Mfrp^rd6-2J
retinal degeneration 6, 2 Jackson
MGI:6794097

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Mfrp^rd6-2J/Mfrp^rd6-2J	B6.Cg-Mfrp^rd6-2J/Boc	MGI:7611788

Allelic Composition	Mfrp^rd6-2J/Mfrp^rd6-2J
Genetic Background	B6.Cg-Mfrp^rd6-2J/Boc

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Mfrp^rd6-2J mutation (1 available); any Mfrp mutation (27 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

vision/eye

retina degeneration ( J:345803 )

retina spots ( J:345803 )

• white retinal dots until approximately 7 months of age when retinal degeneration becomes clinically evident

decreased a-wave amplitude ( J:345803 )

• very small a-wave by 4 weeks of age

decreased b-wave amplitude ( J:345803 )

• reduced to approximately half normal by 4 weeks of age

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
fundus albipunctatus		DOID:11105	OMIM:136880	J:345803

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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