Phenotypes associated with this allele

• Allele Symbol: Garin1a^em1Osb
• Allele Name: endonuclease-mediated mutation 1, Research Institute for Microbial Diseases, Osaka University
• Allele ID: MGI:6825733
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Garin1a^em1Osb/Garin1a^em1Osb	involves: C57BL/6NJcl * DBA/2NJcl	MGI:6827134

Genotype
MGI:6827134

hm1

• Allelic Composition: Garin1a^em1Osb/Garin1a^em1Osb
• Genetic Background: involves: C57BL/6NJcl * DBA/2NJcl

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

reproductive system

abnormal sperm head morphology ( J:314135 )

• mild hook-like structures at the apical sperm head

abnormal acrosome morphology ( J:314135 )

• slightly expanded crescent shape

• however, mitochondria morphology is normal

reduced male fertility ( J:314135 )

impaired fertilization ( J:314135 )

• decreased fertilization of cumulus-intact and cumulus-free oocytes

• however, fertilization of zona pellucida-free oocytes is normal

cellular

abnormal sperm head morphology ( J:314135 )

• mild hook-like structures at the apical sperm head

abnormal acrosome morphology ( J:314135 )

• slightly expanded crescent shape

• however, mitochondria morphology is normal