Phenotypes associated with this allele

• Allele Symbol: Armc3^em1Lukf
• Allele Name: endonuclease-mediated mutation 1, Kefeng Lu
• Allele ID: MGI:6828763
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Armc3^em1Lukf/Armc3^em1Lukf	C57BL/6J-Armc3^em1Lukf	MGI:6828773

Genotype
MGI:6828773

hm1

• Allelic Composition: Armc3^em1Lukf/Armc3^em1Lukf
• Genetic Background: C57BL/6J-Armc3^em1Lukf

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

reproductive system

oligozoospermia ( J:308934 )

♂ • in the cauda epididymis

abnormal spermatid morphology ( J:308934 )

♂ • failure of ribosome removal in elongated spermatids

immotile sperm ( J:308934 )

♂ • with low energy level mitochondria

male infertility ( J:308934 )

♂

homeostasis/metabolism

impaired autophagy ( J:308934 )

• blocked in spermatids

• reduced in mouse embryonic fibroblasts

cellular

oligozoospermia ( J:308934 )

♂ • in the cauda epididymis

abnormal spermatid morphology ( J:308934 )

♂ • failure of ribosome removal in elongated spermatids

impaired autophagy ( J:308934 )

• blocked in spermatids

• reduced in mouse embryonic fibroblasts

immotile sperm ( J:308934 )

♂ • with low energy level mitochondria