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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Nup210tm1Mdan
targeted mutation 1, Maximiliano A D'Angelo
MGI:6830910
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
cn1
 		Nup210tm1Mdan/Nup210tm1Mdan
Tg(Cd4-cre/ERT2)11Gnri/0 		involves: 129X1/SvJ * C57BL/6 MGI:6830956


Genotype
MGI:6830956
cn1
Allelic
Composition		 Nup210tm1Mdan/Nup210tm1Mdan
Tg(Cd4-cre/ERT2)11Gnri/0
Genetic
Background		 involves: 129X1/SvJ * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Nup210tm1Mdan mutation (0 available); any Nup210 mutation (85 available)
Tg(Cd4-cre/ERT2)11Gnri mutation (1 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hematopoietic system
abnormal CD4-positive, alpha-beta T cell physiology ( J:282451 )
• cell-intrinsic reduction in naive CD4+ T cell survival in the periphery in tamoxifen-treated mice

immune system
abnormal CD4-positive, alpha-beta T cell physiology ( J:282451 )
• cell-intrinsic reduction in naive CD4+ T cell survival in the periphery in tamoxifen-treated mice




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory