About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Cenpvtm1c(EUCOMM)Hmgu
targeted mutation 1c, Helmholtz Zentrum Muenchen GmbH
MGI:6838381
Summary 3 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
cn1
 		Cenpvtm1c(EUCOMM)Hmgu/Cenpvtm1c(EUCOMM)Hmgu
Tg(Spo11-cre)1Rsw/0 		involves: C57BL/6N MGI:6838389
cn2
 		Cenpvtm1c(EUCOMM)Hmgu/Cenpvtm1c(EUCOMM)Hmgu
Tg(Ddx4-cre)1Dcas/0 		involves: C57BL/6N * FVB MGI:6838392
cn3
 		Cenpvtm1c(EUCOMM)Hmgu/Cenpvtm1c(EUCOMM)Hmgu
Tg(Stra8-icre)1Reb/0 		involves: C57BL/6N * FVB/NJ MGI:6838391


Genotype
MGI:6838389
cn1
Allelic
Composition		 Cenpvtm1c(EUCOMM)Hmgu/Cenpvtm1c(EUCOMM)Hmgu
Tg(Spo11-cre)1Rsw/0
Genetic
Background		 involves: C57BL/6N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cenpvtm1c(EUCOMM)Hmgu mutation (0 available); any Cenpv mutation (60 available)
Tg(Spo11-cre)1Rsw mutation (1 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
reproductive system
impaired polar body extrusion ( J:314905 )
• decrease in polar body extrusion

cellular
impaired polar body extrusion ( J:314905 )
• decrease in polar body extrusion




Genotype
MGI:6838392
cn2
Allelic
Composition		 Cenpvtm1c(EUCOMM)Hmgu/Cenpvtm1c(EUCOMM)Hmgu
Tg(Ddx4-cre)1Dcas/0
Genetic
Background		 involves: C57BL/6N * FVB
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cenpvtm1c(EUCOMM)Hmgu mutation (0 available); any Cenpv mutation (60 available)
Tg(Ddx4-cre)1Dcas mutation (2 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
reproductive system
abnormal female meiosis ( J:314905 )
• as in other mice carrying the conditional allele activated in oocytes by Tg(Stra8-icre)1Reb or Tg(Spo11-cre)1Rsw

cellular
abnormal female meiosis ( J:314905 )
• as in other mice carrying the conditional allele activated in oocytes by Tg(Stra8-icre)1Reb or Tg(Spo11-cre)1Rsw




Genotype
MGI:6838391
cn3
Allelic
Composition		 Cenpvtm1c(EUCOMM)Hmgu/Cenpvtm1c(EUCOMM)Hmgu
Tg(Stra8-icre)1Reb/0
Genetic
Background		 involves: C57BL/6N * FVB/NJ
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cenpvtm1c(EUCOMM)Hmgu mutation (0 available); any Cenpv mutation (60 available)
Tg(Stra8-icre)1Reb mutation (2 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
reproductive system
impaired polar body extrusion ( J:314905 )
• decrease in polar body extrusion

cellular
impaired polar body extrusion ( J:314905 )
• decrease in polar body extrusion




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
08/02/2024
MGI 6.24 		The Jackson Laboratory