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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Zfp82tm1.1Cya
targeted mutation 1.1, Cyagen Biosciences
MGI:6849761
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
cn1
 		Tg(CDX2-cre/ERT2)752Erf/0
Zfp82tm1.1Cya/Zfp82tm1.1Cya 		involves: 129S4/SvJaeSor * C57BL/6J * C57BL/6NTac MGI:6849773


Genotype
MGI:6849773
cn1
Allelic
Composition		 Tg(CDX2-cre/ERT2)752Erf/0
Zfp82tm1.1Cya/Zfp82tm1.1Cya
Genetic
Background		 involves: 129S4/SvJaeSor * C57BL/6J * C57BL/6NTac
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tg(CDX2-cre/ERT2)752Erf mutation (2 available)
Zfp82tm1.1Cya mutation (0 available); any Zfp82 mutation (29 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
neoplasm
increased incidence of induced tumors ( J:316087 )
• in an AOM/DSS model, tamoxifen-treated mice exhibit increased tumors number and burden compared to control mice
• however, Pol I inhibitor suppresses increased tumor growth




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory