Phenotypes associated with this allele

• Allele Symbol: Lncbar^em1Bcgen
• Allele Name: endonuclease-mediated mutation 1, Biocytogen LLC
• Allele ID: MGI:6866922
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Lncbar^em1Bcgen/Lncbar^em1Bcgen	involves: C57BL/6	MGI:6866932

Genotype
MGI:6866932

hm1

• Allelic Composition: Lncbar^em1Bcgen/Lncbar^em1Bcgen
• Genetic Background: involves: C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

nervous system

increased neuron apoptosis ( J:316179 )

• of intermediate (basal) progenitors in the neocortices

abnormal neocortex morphology ( J:316179 )

• fewer excitatory/projection neurons at E15.5 in deeper regions

increased neuronal precursor cell number ( J:316179 )

• increased intermediate (basal) progenitors that stall during cell cycle progression in the neocortices

• however, overexpression of ZBTB20 restores cell cycle progression

cellular

increased neuron apoptosis ( J:316179 )

• of intermediate (basal) progenitors in the neocortices