All Phenotypes Fam209<em2Osb> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Fam209^em2Osb
endonuclease-mediated mutation 2, Research Institute for Microbial Diseases, Osaka University
MGI:6866939

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Fam209^em2Osb/Fam209^em2Osb	involves: C57BL/6NJcl * DBA/2NJcl	MGI:6866950

Allelic Composition	Fam209^em2Osb/Fam209^em2Osb
Genetic Background	involves: C57BL/6NJcl * DBA/2NJcl

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Fam209^em2Osb mutation (2 available); any Fam209 mutation (24 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

reproductive system

reproductive system phenotype ( J:319865 )

• female mice exhibit normal fertility

abnormal acrosome morphology ( J:319865 )

globozoospermia ( J:319865 )

asthenozoospermia ( J:319865 )

• reduced average path, straight-line and curvilinear velocities that is more severe than in Fam209^em2Osb homozygotes

male infertility ( J:319865 )

• one out of 5 males sired 2 pups

cellular

abnormal acrosome morphology ( J:319865 )

globozoospermia ( J:319865 )

asthenozoospermia ( J:319865 )

• reduced average path, straight-line and curvilinear velocities that is more severe than in Fam209^em2Osb homozygotes

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