Phenotypes associated with this allele

• Allele Symbol: Rad51ap2^em1Qsh
• Allele Name: endonuclease-mediated mutation 1, Qinghua Shi
• Allele ID: MGI:6888019
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Rad51ap2^em1Qsh/Rad51ap2^em1Qsh	involves: C57BL/6J * DBA/2J	MGI:6888119

Genotype
MGI:6888119

hm1

• Allelic Composition: Rad51ap2^em1Qsh/Rad51ap2^em1Qsh
• Genetic Background: involves: C57BL/6J * DBA/2J

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

reproductive system

reproductive system phenotype ( J:321708 )

♀N • crossover formation and meiosis in oocytes is normal

oligozoospermia ( J:321708 )

♂

abnormal X-Y chromosome synapsis during male meiosis ( J:321708 )

♂ • increased frequency of XY dissociation in meiotic metaphase I spermatocytes with reduced crossover and compromised double-strand break repair in the pseudoautosomal region

arrest of male meiosis ( J:321708 )

♂ • unaligned chromosomes and reduced number of post-meiotic germ cells

increased male germ cell apoptosis ( J:321708 )

♂

decreased testis weight ( J:321708 )

♂

endocrine/exocrine glands

decreased testis weight ( J:321708 )

♂

cellular

oligozoospermia ( J:321708 )

♂

abnormal X-Y chromosome synapsis during male meiosis ( J:321708 )

♂ • increased frequency of XY dissociation in meiotic metaphase I spermatocytes with reduced crossover and compromised double-strand break repair in the pseudoautosomal region

arrest of male meiosis ( J:321708 )

♂ • unaligned chromosomes and reduced number of post-meiotic germ cells

increased male germ cell apoptosis ( J:321708 )

♂