Phenotypes associated with this allele

• Allele Symbol: Pxmp4^em1Jwjk
• Allele Name: endonuclease-mediated mutation 1, Johan W Jonker
• Allele ID: MGI:7258107
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Pxmp4^em1Jwjk/Pxmp4^em1Jwjk	B6.FVB-Pxmp4^em1Jwjk	MGI:7261341

Genotype
MGI:7261341

hm1

• Allelic Composition: Pxmp4^em1Jwjk/Pxmp4^em1Jwjk
• Genetic Background: B6.FVB-Pxmp4^em1Jwjk

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

homeostasis/metabolism

homeostasis/metabolism phenotype ( J:322224 )

N • mice exhibit normal very long-chain fatty acids, bile acids, and bile acids intermediates di- and trihydroxycholestanoic acid

abnormal homeostasis ( J:322224 )

• elevated levels of phytol metabolites phytanic and pristanic acid in the liver

• however, supplementation with a phytol-enriched diets exhibit no further increase phytanic/pristanic acid levels

• mildly elevated phytanic acid levels in the liver when fed a standard chow

growth/size/body

growth/size/body region phenotype ( J:322224 )

N • mice fed standard chow exhibit normal body weight and fat mass