Phenotypes associated with this allele

• Allele Symbol: Cep128^em3Fzh
• Allele Name: endonuclease-mediated mutation 3, Feng Zhang
• Allele ID: MGI:7261354
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Cep128^em3Fzh/Cep128^em3Fzh	C57BL/6-Cep128^em3Fzh	MGI:7261360

Genotype
MGI:7261360

hm1

• Allelic Composition: Cep128^em3Fzh/Cep128^em3Fzh
• Genetic Background: C57BL/6-Cep128^em3Fzh

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

reproductive system

reproductive system phenotype ( J:323071 )

♀N

asthenozoospermia ( J:323071 )

♂

abnormal spermatogenesis ( J:323071 )

♂

oligozoospermia ( J:323071 )

♂ • reduced numbers of spermatocytes, round spermatids, and elongating/elongated spermatids

teratozoospermia ( J:323071 )

♂

abnormal sperm axoneme morphology ( J:323071 )

♂ • irregular arrangement of the microtubule doublets 1-3 and outer dense fibers 1-3 in the midpiece

♂ • however, the principal and end pieces exhibit the classic 9+2 configuration

hairpin sperm flagellum ( J:323071 )

♂ • between the midpiece and principal piece

male infertility ( J:323071 )

♂

decreased fertilization frequency ( J:323071 )

♂ • poor fertilization of intracytoplasmic sperm injection

cellular

oligozoospermia ( J:323071 )

♂ • reduced numbers of spermatocytes, round spermatids, and elongating/elongated spermatids

teratozoospermia ( J:323071 )

♂

abnormal sperm axoneme morphology ( J:323071 )

♂ • irregular arrangement of the microtubule doublets 1-3 and outer dense fibers 1-3 in the midpiece

♂ • however, the principal and end pieces exhibit the classic 9+2 configuration

hairpin sperm flagellum ( J:323071 )

♂ • between the midpiece and principal piece

asthenozoospermia ( J:323071 )

♂