Phenotypes associated with this allele

• Allele Symbol: Thada^em1Zsg
• Allele Name: endonuclease-mediated mutation 1, Shi-Gang Zhao
• Allele ID: MGI:7275233
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Thada^em1Zsg/Thada^em1Zsg	C57BL/6J-Thada^em1Zsg	MGI:7275235

Genotype
MGI:7275235

hm1

• Allelic Composition: Thada^em1Zsg/Thada^em1Zsg
• Genetic Background: C57BL/6J-Thada^em1Zsg

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

normal phenotype

no abnormal phenotype detected ( J:324168 )

• development of mice appears normal from birth to adulthood

reproductive system

reproductive system phenotype ( J:324168 )

♀N • mice exhibit normal fertility, litter size and the number of males/females per litter no detectable ovarian dysfunction is seen in mice fed a normal diet and females show normal anogenital distance, time of first estrus, estrous cyclicity and cycle length, ovarian weights, pubertal development. proportions of follicles at different stages, serum estrogen and progesterone levels and no alteration in the number of oocytes or PB1 extrusion rate in superovulated females

♀N • mice fed a high-fat-high-sugar diet show no differences in body weight compared to wild-type mice and little change in ovarian morphology and structure or estrous cycle