Analysis Tools
normal phenotype
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• development of mice appears normal from birth to adulthood
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reproductive system
 N |
• mice exhibit normal fertility, litter size and the number of males/females per litter
no detectable ovarian dysfunction is seen in mice fed a normal diet and females show normal anogenital distance, time of first estrus, estrous cyclicity and cycle length, ovarian weights, pubertal development. proportions of follicles at different stages, serum estrogen and progesterone levels and no alteration in the number of oocytes or PB1 extrusion rate in superovulated females
• mice fed a high-fat-high-sugar diet show no differences in body weight compared to wild-type mice and little change in ovarian morphology and structure or estrous cycle
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