Phenotypes associated with this allele

• Allele Symbol: Vwde^em1Iwto
• Allele Name: endonuclease-mediated mutation 1, Tsutomu Iwamoto
• Allele ID: MGI:7286448
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Vwde^em1Iwto/Vwde^em1Iwto	C57BL/6-Vwde^em1Iwto	MGI:7286450

Genotype
MGI:7286450

hm1

• Allelic Composition: Vwde^em1Iwto/Vwde^em1Iwto
• Genetic Background: C57BL/6-Vwde^em1Iwto

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

craniofacial

abnormal molar morphology ( J:324628 )

• rough surface and frequent cracked lines with increased frequency of cracked molars

abnormal tooth color ( J:324628 )

• slight change in coloration

abnormal enamel morphology ( J:324628 )

• segments 5 through 11 exhibit reduced enamel mineral density compared with wild-type mice

• reduced total enamel mineral density

• however, segments 1 through 4 exhibit normal enamel mineral density

growth/size/body

abnormal molar morphology ( J:324628 )

• rough surface and frequent cracked lines with increased frequency of cracked molars

abnormal tooth color ( J:324628 )

• slight change in coloration

abnormal enamel morphology ( J:324628 )

• segments 5 through 11 exhibit reduced enamel mineral density compared with wild-type mice

• reduced total enamel mineral density

• however, segments 1 through 4 exhibit normal enamel mineral density

skeleton

abnormal molar morphology ( J:324628 )

• rough surface and frequent cracked lines with increased frequency of cracked molars

abnormal tooth color ( J:324628 )

• slight change in coloration

abnormal enamel morphology ( J:324628 )

• segments 5 through 11 exhibit reduced enamel mineral density compared with wild-type mice

• reduced total enamel mineral density

• however, segments 1 through 4 exhibit normal enamel mineral density