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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Uba1em1Imat
endonuclease-mediated mutation 1, Isao Matsuo
MGI:7287390
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
cx1
 		Uba1em1Imat/Uba1+
Usp39em1Imat/Usp39em1Imat 		CD1-Usp39em1Imat Uba1em1Imat MGI:7287418
ot2
 		Uba1em1Imat/Y CD1-Uba1em1Imat MGI:7287416


Genotype
MGI:7287418
cx1
Allelic
Composition		 Uba1em1Imat/Uba1+
Usp39em1Imat/Usp39em1Imat
Genetic
Background		 CD1-Usp39em1Imat Uba1em1Imat
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Uba1em1Imat mutation (0 available); any Uba1 mutation (6 available)
Usp39em1Imat mutation (0 available); any Usp39 mutation (26 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
embryo
abnormal primitive streak formation ( J:324183 )
• partial at E6.5 with mesoderm cells migrating toward the anterior side unlike in Usp39em1Imat homozygotes




Genotype
MGI:7287416
ot2
Allelic
Composition		 Uba1em1Imat/Y
Genetic
Background		 CD1-Uba1em1Imat
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Uba1em1Imat mutation (0 available); any Uba1 mutation (6 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
embryonic lethality at implantation, complete penetrance ( J:324183 )
• mice exhibit peri-implantation lethality

embryo
abnormal embryo morphology ( J:324183 )
• at the blastocyst stage




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory