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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Cntlnem1Wli
endonuclease-mediated mutation 1, Wei Li
MGI:7287464
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Cntlnem1Wli/Cntlnem1Wli involves: C57BL/6J * DBA/2J MGI:7287465


Genotype
MGI:7287465
hm1
Allelic
Composition		 Cntlnem1Wli/Cntlnem1Wli
Genetic
Background		 involves: C57BL/6J * DBA/2J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cntlnem1Wli mutation (0 available); any Cntln mutation (75 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
reproductive system
absent sperm head ( J:324173 )
• due to impaired head to tail anchorage of spermatids
male infertility ( J:324173 )
• male mice fail to sire offspring
• however, male mice exhibit normal mating behavior, copulation, meiosis, and acrosome biogenesis

cellular
absent sperm head ( J:324173 )
• due to impaired head to tail anchorage of spermatids




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
10/09/2024
MGI 6.24 		The Jackson Laboratory