About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Tnfrsf1aem2Smoc
endonuclease-mediated mutation 2, Shanghai Model Organisms Center
MGI:7292882
Summary 1 genotype


Genotype
MGI:7568799
cx1
Allelic
Composition
Tnfaip8l1em1Huwa/Tnfaip8l1em1Huwa
Tnfrsf1aem2Smoc/Tnfrsf1aem2Smoc
Tnfrsf1bem1Smoc/Tnfrsf1bem1Smoc
Genetic
Background
C57BL/6-Tnfrsf1bem1Smoc Tnfrsf1aem2Smoc Tnfaip8l1em1Huwa
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tnfaip8l1em1Huwa mutation (0 available); any Tnfaip8l1 mutation (12 available)
Tnfrsf1aem2Smoc mutation (0 available); any Tnfrsf1a mutation (52 available)
Tnfrsf1bem1Smoc mutation (0 available); any Tnfrsf1b mutation (41 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
digestive/alimentary system
N
• mice show similar DSS-induced colitis as wild-type mice but less severe colitis symptoms than single Tnfaip8l1 homozygotes





Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
10/29/2024
MGI 6.24
The Jackson Laboratory