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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Tnfrsf1aem2Smoc
endonuclease-mediated mutation 2, Shanghai Model Organisms Center
MGI:7292882
Summary 1 genotype


Genotype
MGI:7568799
cx1
Allelic
Composition
Tnfaip8l1em1Huwa/Tnfaip8l1em1Huwa
Tnfrsf1aem2Smoc/Tnfrsf1aem2Smoc
Tnfrsf1bem1Smoc/Tnfrsf1bem1Smoc
Genetic
Background
C57BL/6-Tnfrsf1bem1Smoc Tnfrsf1aem2Smoc Tnfaip8l1em1Huwa
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tnfaip8l1em1Huwa mutation (0 available); any Tnfaip8l1 mutation (12 available)
Tnfrsf1aem2Smoc mutation (0 available); any Tnfrsf1a mutation (52 available)
Tnfrsf1bem1Smoc mutation (0 available); any Tnfrsf1b mutation (41 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
digestive/alimentary system
N
• mice show similar DSS-induced colitis as wild-type mice but less severe colitis symptoms than single Tnfaip8l1 homozygotes





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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory