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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Lrrc55em3Gpt
endonuclease-mediated mutation 3, GemPharmatech Co., Ltd
MGI:7301779
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Lrrc55em3Gpt/Lrrc55em3Gpt involves: C57BL/6JGpt MGI:7639923


Genotype
MGI:7639923
hm1
Allelic
Composition		 Lrrc55em3Gpt/Lrrc55em3Gpt
Genetic
Background		 involves: C57BL/6JGpt
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Lrrc55em3Gpt mutation (0 available); any Lrrc55 mutation (19 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
renal/urinary system
abnormal renal protein reabsorption ( J:325255 )
• attenuation of the increase in the rate of angiotensin II (Ang II)-induced albumin excretion
abnormal podocyte morphology ( J:325255 )
• attenuation of Ang II-induced focal segmental lesions and foot process effacement
abnormal podocyte physiology ( J:325255 )
• inhibition of Ang II-induced activation of big-conductance Ca2+-activated K+ (BK) channels

homeostasis/metabolism
abnormal renal protein reabsorption ( J:325255 )
• attenuation of the increase in the rate of angiotensin II (Ang II)-induced albumin excretion




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
10/09/2024
MGI 6.24 		The Jackson Laboratory