Phenotypes associated with this allele

• Allele Symbol: Smyd3^em1Yzzh
• Allele Name: endonuclease-mediated mutation 1, Yi Zhun Zhu
• Allele ID: MGI:7310439
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Smyd3^em1Yzzh/Smyd3^em1Yzzh	C57BL/6-Smyd3^em1Yzzh	MGI:7310444

Genotype
MGI:7310444

hm1

• Allelic Composition: Smyd3^em1Yzzh/Smyd3^em1Yzzh
• Genetic Background: C57BL/6-Smyd3^em1Yzzh

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

cardiovascular system

abnormal aorta wall morphology ( J:296379 )

• Ang II-treated mice exhibit alleviated senescence-related thinning of the aorta compared with wild-type mice

abnormal systemic arterial blood pressure ( J:296379 )

• Ang II-treated mice exhibit decreased systolic blood pressure compared with wild-type mice

abnormal vasodilation ( J:296379 )

• Ang II-treated mice exhibit improved acetylcholine-induced endothelial-dependent relaxation compared with wild-type mice

homeostasis/metabolism

abnormal response/metabolism to endogenous compounds ( J:296379 )

• Ang II-treated mice exhibit alleviated senescence-related phenotypes in the arteries, decreased systolic blood pressure, and improved acetylcholine-induced endothelial-dependent relaxation compared with wild-type mice

muscle

abnormal vasodilation ( J:296379 )

• Ang II-treated mice exhibit improved acetylcholine-induced endothelial-dependent relaxation compared with wild-type mice