Phenotypes associated with this allele

• Allele Symbol: Cemip^tm1.1Okda
• Allele Name: targeted mutation 1.1, Yasunori Okada
• Allele ID: MGI:7311628
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Cemip^tm1.1Okda/Cemip^tm1.1Okda	involves: C57BL/6NCrlj * CBA/JNCrlj	MGI:7311661

Genotype
MGI:7311661

hm1

• Allelic Composition: Cemip^tm1.1Okda/Cemip^tm1.1Okda
• Genetic Background: involves: C57BL/6NCrlj * CBA/JNCrlj

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

prenatal lethality, incomplete penetrance ( J:241936 )

• fewer than expected mice are born

skeleton

decreased osteoclast cell number ( J:241936 )

short femur ( J:241936 )

• at 8 weeks of age

short tibia ( J:241936 )

• at 8 weeks of age

increased long bone epiphyseal plate size ( J:241936 )

• at 2 weeks of age

limbs/digits/tail

short femur ( J:241936 )

• at 8 weeks of age

short tibia ( J:241936 )

• at 8 weeks of age

immune system

decreased osteoclast cell number ( J:241936 )

hematopoietic system

decreased osteoclast cell number ( J:241936 )

cardiovascular system

decreased angiogenesis ( J:241936 )

• at the chondroosseous junction without a change in VEGF production