Phenotypes associated with this allele

• Allele Symbol: Gt(ROSA)26Sor^{tm3(CAG-Shox2)Fawa}
• Allele Name: targeted mutation 3, Fan Wang
• Allele ID: MGI:7314722
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
cn1	Gt(ROSA)26Sor^tm3(CAG-Shox2)Fawa/Gt(ROSA)26Sor^+ H2az2^Tg(Wnt1-cre)11Rth/H2az2^+ Meis2^tm1.1Zkoz/Meis2^tm1.1Zkoz	involves: 129S6/SvEvTac * C57BL/6J * CBA/J	MGI:7335081

Genotype
MGI:7335081

cn1

• Allelic Composition: Gt(ROSA)26Sor^{tm3(CAG-Shox2)Fawa}/Gt(ROSA)26Sor⁺; H2az2^{Tg(Wnt1-cre)11Rth}/H2az2⁺; Meis2^tm1.1Zkoz/Meis2^tm1.1Zkoz
• Genetic Background: involves: 129S6/SvEvTac * C57BL/6J * CBA/J

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

neonatal lethality, complete penetrance ( J:286823 )

craniofacial

absent palate bones ( J:286823 )

• complete absence of palatal bones in all mice

cleft secondary palate ( J:286823 )

• complete cleft is seen in 9 of 14

submucous cleft palate ( J:286823 )

• in 5 of 14

• manifests as fused anterior palate and cleft soft palate

skeleton

absent palate bones ( J:286823 )

• complete absence of palatal bones in all mice

digestive/alimentary system

absent palate bones ( J:286823 )

• complete absence of palatal bones in all mice

cleft secondary palate ( J:286823 )

• complete cleft is seen in 9 of 14

submucous cleft palate ( J:286823 )

• in 5 of 14

• manifests as fused anterior palate and cleft soft palate

growth/size/body

absent palate bones ( J:286823 )

• complete absence of palatal bones in all mice

cleft secondary palate ( J:286823 )

• complete cleft is seen in 9 of 14

submucous cleft palate ( J:286823 )

• in 5 of 14

• manifests as fused anterior palate and cleft soft palate