All Phenotypes Cep250<em1Glvr> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Cep250^em1Glvr
endonuclease-mediated mutation 1, Gabriel Livera
MGI:7327530

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Cep250^em1Glvr/Cep250^em1Glvr	C57BL/6-Cep250^em1Glvr	MGI:7327533

Allelic Composition	Cep250^em1Glvr/Cep250^em1Glvr
Genetic Background	C57BL/6-Cep250^em1Glvr

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cep250^em1Glvr mutation (0 available); any Cep250 mutation (98 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

reproductive system

reproductive system phenotype ( J:324876 )

N	• female mice exhibit normal meiosis

azoospermia ( J:324876 )

• complete absence of spermatids and spermatozoa in the seminiferous tubules

arrest of male meiosis ( J:324876 )

• meiosis arrest in prophase I with reduced leptotene and zygotene cells at 10 dpp

• however, germ cells exhibit normal mitosis to meiosis switch

small testis ( J:324876 )

male infertility ( J:324876 )

cellular