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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Prmt1tm1Hkim
targeted mutation 1, Hail Kim
MGI:7327647
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
cn1
 		Prmt1tm1Hkim/Prmt1tm1Hkim
Tg(Neurog3-cre)24Syos/0 		Not Specified MGI:7327649


Genotype
MGI:7327649
cn1
Allelic
Composition		 Prmt1tm1Hkim/Prmt1tm1Hkim
Tg(Neurog3-cre)24Syos/0
Genetic
Background		 Not Specified
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Prmt1tm1Hkim mutation (0 available); any Prmt1 mutation (35 available)
Tg(Neurog3-cre)24Syos mutation (1 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
reproductive system
reproductive system phenotype ( J:324166 )
N
• female mice exhibit normal fertility
arrest of male meiosis ( J:324166 )
• at the leptotene or zygotene stage with accumulation of double strand breaks
seminiferous tubule degeneration ( J:324166 )
• atrophic from P14 onward
small testis ( J:324166 )
• from P14 onward

endocrine/exocrine glands
seminiferous tubule degeneration ( J:324166 )
• atrophic from P14 onward
small testis ( J:324166 )
• from P14 onward

cellular
arrest of male meiosis ( J:324166 )
• at the leptotene or zygotene stage with accumulation of double strand breaks




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory