Phenotypes associated with this allele

• Allele Symbol: Gt(ROSA)26Sor^{em#(CAG-Fstl5)Jrio}
• Allele Name: endonuclease-mediated mutation, Jonathan J Rios
• Allele ID: MGI:7331585
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
cn1	Gt(ROSA)26Sor^em#(CAG-Fstl5)Jrio/Gt(ROSA)26Sor^+ Tg(Prrx1-cre)1Cjt/0	involves: C57BL/6J * C57BL/6N * SJL/J	MGI:7331609

Genotype
MGI:7331609

cn1

• Allelic Composition: Gt(ROSA)26Sor^{em#(CAG-Fstl5)Jrio}/Gt(ROSA)26Sor⁺; Tg(Prrx1-cre)1Cjt/0
• Genetic Background: involves: C57BL/6J * C57BL/6N * SJL/J

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

skeleton

short femur ( J:301587 )

♂ • femur lengths are slightly, but significantly, reduced in 3-month-old males but not in females

short tibia ( J:301587 )

♂ • tibia lengths are slightly, but significantly, reduced in 3-month-old males but not females

abnormal bone mineral density ( J:301587 )

♂ • tibia bone mineral density is reduced in males but not females

decreased bone mineral density of femur ( J:301587 )

♂ • femur bone mineral density is reduced in males but not females

limbs/digits/tail

short femur ( J:301587 )

♂ • femur lengths are slightly, but significantly, reduced in 3-month-old males but not in females

short tibia ( J:301587 )

♂ • tibia lengths are slightly, but significantly, reduced in 3-month-old males but not females