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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Pgbd5tm1.1Aken
targeted mutation 1.1, Alex Kentsis
MGI:7334716
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
cn1
Pgbd5tm1.1Aken/Pgbd5tm1.2Aken
Ptch1tm1Bjw/Ptch1tm1Bjw
Ptf1atm1.1(cre)Cvw/Ptf1a+
involves: 129 * C57BL/6J * C57BL/6NTac * FVB/N * SW MGI:7616728
cn2
Gt(ROSA)26Sortm1(Smo/EYFP)Amc/Gt(ROSA)26Sortm2(EGFP/cre)Alj
Pgbd5tm1.1Aken/Pgbd5tm1.1Aken
involves: 129 * C57BL/6J * C57BL/6NTac * SW MGI:7616743


Genotype
MGI:7616728
cn1
Allelic
Composition
Pgbd5tm1.1Aken/Pgbd5tm1.2Aken
Ptch1tm1Bjw/Ptch1tm1Bjw
Ptf1atm1.1(cre)Cvw/Ptf1a+
Genetic
Background
involves: 129 * C57BL/6J * C57BL/6NTac * FVB/N * SW
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Pgbd5tm1.1Aken mutation (1 available); any Pgbd5 mutation (35 available)
Pgbd5tm1.2Aken mutation (0 available); any Pgbd5 mutation (35 available)
Ptch1tm1Bjw mutation (2 available); any Ptch1 mutation (115 available)
Ptf1atm1.1(cre)Cvw mutation (1 available); any Ptf1a mutation (31 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
neoplasm
• develop tumors with a similar latency to mice with one wild-type Pgbd5 allele, but most tumors retain an unrecombined floxed Pgbd5 allele

nervous system
• develop tumors with a similar latency to mice with one wild-type Pgbd5 allele, but most tumors retain an unrecombined floxed Pgbd5 allele




Genotype
MGI:7616743
cn2
Allelic
Composition
Gt(ROSA)26Sortm1(Smo/EYFP)Amc/Gt(ROSA)26Sortm2(EGFP/cre)Alj
Pgbd5tm1.1Aken/Pgbd5tm1.1Aken
Genetic
Background
involves: 129 * C57BL/6J * C57BL/6NTac * SW
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gt(ROSA)26Sortm1(Smo/EYFP)Amc mutation (1 available); any Gt(ROSA)26Sor mutation (993 available)
Gt(ROSA)26Sortm2(EGFP/cre)Alj mutation (2 available); any Gt(ROSA)26Sor mutation (993 available)
Pgbd5tm1.1Aken mutation (1 available); any Pgbd5 mutation (35 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
neoplasm
• develop tumors with a similar latency to mice with one wild-type Pgbd5 allele, but most tumors retain an unrecombined floxed Pgbd5 allele

nervous system
• develop tumors with a similar latency to mice with one wild-type Pgbd5 allele, but most tumors retain an unrecombined floxed Pgbd5 allele





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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory