Phenotypes associated with this allele

• Allele Symbol: Dino^tm1.1Hyc
• Allele Name: targeted mutation 1.1, Howard Chang
• Allele ID: MGI:7335151
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Dino^tm1.1Hyc/Dino^tm1.1Hyc	involves: C57BL/6	MGI:7335153

Genotype
MGI:7335153

hm1

• Allelic Composition: Dino^tm1.1Hyc/Dino^tm1.1Hyc
• Genetic Background: involves: C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

decreased mortality induced by ionizing radiation ( J:259337 )

cellular

decreased cellular sensitivity to gamma-irradiation ( J:259337 )

• reduced apoptosis and enhanced survival of thymocytes (even CD4+CD8+ thymocytes) exposed to gamma radiation

homeostasis/metabolism

decreased mortality induced by ionizing radiation ( J:259337 )