Phenotypes associated with this allele

• Allele Symbol: Rr277^em1Flc
• Allele Name: endonuclease-mediated mutation 1, Frank Conlon
• Allele ID: MGI:7341596
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Rr277^em1Flc/Rr277^em1Flc	C57BL/6J-Rr277^em1Flc	MGI:7341735

Genotype
MGI:7341735

hm1

• Allelic Composition: Rr277^em1Flc/Rr277^em1Flc
• Genetic Background: C57BL/6J-Rr277^em1Flc

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

cardiovascular system

thick myocardium compact layer ( J:324708 )

• in right ventricle in E12.5 and E16.5 embryos

abnormal heart ventricle morphology ( J:324708 )

• fewer myocardial trabecula in E12.5 embryos

thin ventricle myocardium compact layer ( J:324708 )

• in left and right ventricle in E10.5 and left ventricle in E12.5 and E16.5 embryos

increased heart right ventricle wall thickness ( J:324708 )

• thick outer wall in E12.5 and E16.5 embryos

thin ventricular wall ( J:324708 )

• thin outer left and right ventricle walls in E10.5 and left ventricle in E12.5 and E16.5 embryos

mortality/aging

lethality throughout fetal growth and development, complete penetrance ( J:324708 )

• embryos observed at E16.5 but no mice born

muscle

thick myocardium compact layer ( J:324708 )

• in right ventricle in E12.5 and E16.5 embryos

thin ventricle myocardium compact layer ( J:324708 )

• in left and right ventricle in E10.5 and left ventricle in E12.5 and E16.5 embryos