Phenotypes associated with this allele

• Allele Symbol: Rr291^tm2.1Mekk
• Allele Name: targeted mutation 2.1, Marc Ekker
• Allele ID: MGI:7356589
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Rr291^tm2.1Mekk/Rr291^tm2.1Mekk	Not Specified	MGI:7356617
cx2	Rr291^tm2.1Mekk/Rr291^tm2.1Mekk Rr293^tm1.1Mekk/Rr293^tm1.1Mekk	Not Specified	MGI:7356619

Genotype
MGI:7356617

hm1

• Allelic Composition: Rr291^tm2.1Mekk/Rr291^tm2.1Mekk
• Genetic Background: Not Specified

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

nervous system

abnormal GABAergic neuron morphology ( J:312374 )

• reduced number in the lateral ganglionic eminence (LGE) in E13.5 embryos

• normal number in somatosensory cortex at age P35

embryo

embryo phenotype ( J:312374 )

• no obvious developmental phenotype

mortality/aging

mortality/aging ( J:312374 )

• viable

behavior/neurological

behavior/neurological phenotype ( J:312374 )

• normal behavior in beam brake, elevated plus maze and open field tests

reproductive system

reproductive system phenotype ( J:312374 )

• fertile

Genotype
MGI:7356619

cx2

• Allelic Composition: Rr291^tm2.1Mekk/Rr291^tm2.1Mekk; Rr293^tm1.1Mekk/Rr293^tm1.1Mekk
• Genetic Background: Not Specified

behavior/neurological

behavior/neurological phenotype ( J:312374 )

N • normal behavior in beam brake, elevated plus maze and open field tests