Phenotypes associated with this allele

• Allele Symbol: Rr296^em1Hzo
• Allele Name: endonuclease-mediated mutation 1, Huda Y Zoghbi
• Allele ID: MGI:7356641
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Rr296^em1Hzo/Rr296^em1Hzo	Not Specified	MGI:7356676

Genotype
MGI:7356676

hm1

• Allelic Composition: Rr296^em1Hzo/Rr296^em1Hzo
• Genetic Background: Not Specified

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

behavior/neurological phenotype ( J:311942 )

N • normal behavior in rotarod test at age 30 weeks

N • normal behavior in three-chamber sociability test at age 24 weeks

N • normal social dominance behavior in tube test at age 30 weeks

N • normal behavior in cued fear conditioning test at age 36 weeks

impaired contextual conditioning behavior ( J:311942 )

• increased freezing at age 36 weeks

increased anxiety-related response ( J:311942 )

• less time spent in and fewer entries into center in open field test at age 9 weeks

• fewer entries into open arms in elevated plus maze test at age 10 weeks

hypoactivity ( J:311942 )

• decreased horizontal activity counts in open field test at age 9 weeks

decreased locomotor activity ( J:311942 )

• shorter distance traveled in open field test at age 9 weeks

nervous system

nervous system phenotype ( J:311942 )

N • normal sensorimotor neuron gating in pre-pulse inhibition assay at age 24 weeks