Allele Symbol Allele Name Allele ID |
Aldh3b2em1Akih endonuclease-mediated mutation 1, Akio Kihara MGI:7367353 |
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Summary |
2 genotypes
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♀ | phenotype observed in females |
♂ | phenotype observed in males |
N | normal phenotype |
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♀ | phenotype observed in females |
♂ | phenotype observed in males |
N | normal phenotype |
• mice do not survive beyond P2 with absent milk spot and left outside of the nest
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• rougher in texture than control mice with shallow sulcus cutis
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• decreased acylceramide levels in the epidermis and stratum corneum
• however, mice exhibit normal levels of protein-bound ceramides in the epidermis
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• increased level of many triglyceride species in the epidermis
• however, total triglyceride levels are normal
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• after birth
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• associated with being left outside of the nest
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Mouse Models of Human Disease |
DO ID | OMIM ID(s) | Ref(s) | |
Sjogren-Larsson syndrome | DOID:14501 |
OMIM:270200 |
J:330263 |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 08/02/2024 MGI 6.24 |
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