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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Rtl5tm1.1Tmki
targeted mutation 1.1, Tomoko Kaneko-Ishino
MGI:7378511
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Rtl5tm1.1Tmki/Rtl5tm1.1Tmki involves: C57BL/6NCrlj * CBA/JNCrlj MGI:7380248
cx2
 		Rtl5tm1.1Tmki/Rtl5tm1.1Tmki
Rtl6tm1.1Tmki/Rtl6tm1.1Tmki 		involves: C57BL/6NCrlj * C57BL/6NSlc * CBA/JNCrlj MGI:7380246


Genotype
MGI:7380248
hm1
Allelic
Composition		 Rtl5tm1.1Tmki/Rtl5tm1.1Tmki
Genetic
Background		 involves: C57BL/6NCrlj * CBA/JNCrlj
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Rtl5tm1.1Tmki mutation (1 available); any Rtl5 mutation (6 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
immune system phenotype ( J:329352 )
N
• mice exhibit normal LPS removal




Genotype
MGI:7380246
cx2
Allelic
Composition		 Rtl5tm1.1Tmki/Rtl5tm1.1Tmki
Rtl6tm1.1Tmki/Rtl6tm1.1Tmki
Genetic
Background		 involves: C57BL/6NCrlj * C57BL/6NSlc * CBA/JNCrlj
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Rtl5tm1.1Tmki mutation (1 available); any Rtl5 mutation (6 available)
Rtl6tm1.1Tmki mutation (1 available); any Rtl6 mutation (10 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
abnormal inflammatory response ( J:329352 )
• abolished dsRNA analog removal




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory