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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Tprkbem1Chuan
endonuclease-mediated mutation 1, Takashi Iwamoto
MGI:7382804
Summary 2 genotypes


Genotype
MGI:7382808
cx1
Allelic
Composition		 In(6)1J/In(6)1J
Mitfem1Chuan/Mitfem1Chuan
Tprkbem1Chuan/Tprkbem1Chuan
Genetic
Background		 B6N.Cg-In(6)1J Tprkbem1Chuan Mitfem1Chuan
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
In(6)1J mutation (3 available); any In(6)1J mutation (2 available)
Mitfem1Chuan mutation (1 available); any Mitf mutation (74 available)
Tprkbem1Chuan mutation (0 available); any Tprkb mutation (13 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
mortality/aging ( J:330636 )
N
• viable mice could be obtained unlike with mice lacking the inversion are electroporated with the guide RNAs




Genotype
MGI:7382810
cx2
Allelic
Composition		 Mitfem1Chuan/Mitfem1Chuan
Tprkbem1Chuan/Tprkbem1Chuan
Genetic
Background		 B6N.Cg-Tprkbem1Chuan Mitfem1Chuan
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Mitfem1Chuan mutation (1 available); any Mitf mutation (74 available)
Tprkbem1Chuan mutation (0 available); any Tprkb mutation (13 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
embryonic lethality, complete penetrance ( J:330636 )
• mice die prior to E7.5




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory