Phenotypes associated with this allele

• Allele Symbol: Gm16364^tm1Zhaoy
• Allele Name: targeted mutation 1, Yun Zhao
• Allele ID: MGI:7386870
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Gm16364^tm1Zhaoy/Gm16364^tm1Zhaoy	involves: C57BL/6	MGI:7386872

Genotype
MGI:7386872

hm1

• Allelic Composition: Gm16364^tm1Zhaoy/Gm16364^tm1Zhaoy
• Genetic Background: involves: C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

homeostasis/metabolism

increased energy expenditure ( J:322340 )

• when fed a high-fat diet compared with similarly treated control mice

decreased susceptibility to diet-induced obesity ( J:322340 )

• when fed a high-fat diet compared with similarly treated control mice

improved glucose tolerance ( J:322340 )

• when fed a high-fat diet compared with similarly treated control mice

increased insulin sensitivity ( J:322340 )

• when fed a high-fat diet compared with similarly treated control mice

liver/biliary system

decreased liver weight ( J:322340 )

• when fed a high-fat diet compared with similarly treated control mice

decreased susceptibility to diet-induced hepatic steatosis ( J:322340 )

• when fed a high-fat diet compared with similarly treated control mice

adipose tissue

decreased fat cell size ( J:322340 )

• when fed a high-fat diet compared with similarly treated control mice

growth/size/body

decreased susceptibility to diet-induced obesity ( J:322340 )

• when fed a high-fat diet compared with similarly treated control mice