Phenotypes associated with this allele

• Allele Symbol: Gm16364^tm2Zhaoy
• Allele Name: targeted mutation 2, Yun Zhao
• Allele ID: MGI:7386871
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Gm16364^tm2Zhaoy/Gm16364^tm2Zhaoy	involves: C57BL/6	MGI:7386873

Genotype
MGI:7386873

hm1

• Allelic Composition: Gm16364^tm2Zhaoy/Gm16364^tm2Zhaoy
• Genetic Background: involves: C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

homeostasis/metabolism

decreased susceptibility to diet-induced obesity ( J:322340 )

• when fed a high-fat diet compared with similarly treated control mice

improved glucose tolerance ( J:322340 )

• when fed a high-fat diet compared with similarly treated control mice

increased insulin sensitivity ( J:322340 )

• when fed a high-fat diet compared with similarly treated control mice

decreased lipogenesis ( J:322340 )

• decreased hepatic de novo lipogenesis activity

liver/biliary system

decreased susceptibility to diet-induced hepatic steatosis ( J:322340 )

• when fed a high-fat diet compared with similarly treated control mice

adipose tissue

decreased white adipose tissue mass ( J:322340 )

• when fed a high-fat diet compared with similarly treated control mice

growth/size/body

decreased susceptibility to diet-induced obesity ( J:322340 )

• when fed a high-fat diet compared with similarly treated control mice