homeostasis/metabolism
• mice fed a high fat diet (HFD) exhibit higher insulin levels
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• mice fed a HFD exhibit worsened glucose tolerance
• however, mice fed a chow diet show no difference in glucose tolerance
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• mice fed a HFD exhibit worsened insulin sensitivity
• however, mice fed a chow diet show no difference in the insulin tolerance test
• mice fed a HFD exhibit a higher Homeostatic Model Assessment (HOMA) of insulin resistance compared to control mice
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adipose tissue
• HFD-fed mice show increased macrophage infiltration in epididymal white adipose tissue (eWAT)
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immune system
• HFD-fed mice show increased macrophage infiltration in epididymal white adipose tissue (eWAT)
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growth/size/body
N |
• mice fed a chow diet show no differences in body weight, body composition, or tissue mass
• mice fed a high fat diet (HFD) show no changes in body weight or body composition or in energy homeostasis compared with controls
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