Phenotypes associated with this allele

• Allele Symbol: Lncenc1^em2Smoc
• Allele Name: endonuclease-mediated mutation 2, Shanghai Model Organisms Center
• Allele ID: MGI:7386899
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Lncenc1^em2Smoc/Lncenc1^em2Smoc	C57BL/6J-Lncenc1^em2Smoc	MGI:7386910

Genotype
MGI:7386910

hm1

• Allelic Composition: Lncenc1^em2Smoc/Lncenc1^em2Smoc
• Genetic Background: C57BL/6J-Lncenc1^em2Smoc

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

homeostasis/metabolism

decreased susceptibility to diet-induced obesity ( J:306153 )

• when mice are fed a high-fat diet

decreased circulating triglyceride level ( J:306153 )

• when mice are fed a high-fat diet

impaired glucose tolerance ( J:306153 )

• when fed normal chow

insulin resistance ( J:306153 )

• when fed normal chow

adipose tissue

decreased total body fat amount ( J:306153 )

• when mice are fed a high-fat diet

decreased brown adipose tissue mass ( J:306153 )

• when mice are fed a high-fat diet

decreased brown fat cell size ( J:306153 )

• when mice are fed a high-fat diet

• however, mice exhibit normal brown fat cell size when fed standard chow

decreased epididymal fat pad weight ( J:306153 )

• when mice are fed a high-fat diet

decreased inguinal fat pad weight ( J:306153 )

• when mice are fed a high-fat diet

growth/size/body

decreased susceptibility to diet-induced obesity ( J:306153 )

• when mice are fed a high-fat diet

behavior/neurological

behavior/neurological phenotype ( J:306153 )

N • mice exhibit normal total daily food consumption when fed standard chow or a high-fat diet

renal/urinary system

renal/urinary system phenotype ( J:306153 )

N • mice exhibit normal liver size