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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Trex1em3Gpt
endonuclease-mediated mutation 3, GemPharmatech Co., Ltd
MGI:7408568
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Trex1em3Gpt/Trex1em3Gpt C57BL/6JGpt-Trex1em3Gpt MGI:7410897


Genotype
MGI:7410897
hm1
Allelic
Composition		 Trex1em3Gpt/Trex1em3Gpt
Genetic
Background		 C57BL/6JGpt-Trex1em3Gpt
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Trex1em3Gpt mutation (0 available); any Trex1 mutation (26 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging

immune system
increased susceptibility to autoimmune disorder ( J:330879 )
• increased immune cell infiltration in the liver, heart, and lung with increased serum levels of TNF, CXCL1. CCL5, and total IgG

growth/size/body
decreased body size ( J:330879 )
decreased body weight ( J:330879 )
enlarged spleen ( J:330879 )
increased spleen weight ( J:330879 )

homeostasis/metabolism

hematopoietic system




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/17/2024
MGI 6.24 		The Jackson Laboratory