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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		S100a4em1(cre)Zhyg
endonuclease-mediated mutation 1, Ying Zhao
MGI:7413867
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
cn1
 		Nufip1em1Cya/Nufip1em1Cya
S100a4em1(cre)Zhyg/S100a4+ 		involves: C57BL/6J MGI:7413886
cn2
 		Atg5em1Smoc/Atg5em1Smoc
S100a4em1(cre)Zhyg/S100a4+ 		involves: C57BL/6J MGI:7413887


Genotype
MGI:7413886
cn1
Allelic
Composition		 Nufip1em1Cya/Nufip1em1Cya
S100a4em1(cre)Zhyg/S100a4+
Genetic
Background		 involves: C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Nufip1em1Cya mutation (0 available); any Nufip1 mutation (34 available)
S100a4em1(cre)Zhyg mutation (0 available); any S100a4 mutation (26 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
neoplasm
neoplasm ( J:330821 )
N
• mice exhibit normal desmoplastic response to pancreatic implantation with murine pancreatic ductal adenocarcinoma cells
decreased tumor growth/size ( J:330821 )
• due to reduced proliferation compared to when murine pancreatic ductal adenocarcinoma cells are implanted into control mice




Genotype
MGI:7413887
cn2
Allelic
Composition		 Atg5em1Smoc/Atg5em1Smoc
S100a4em1(cre)Zhyg/S100a4+
Genetic
Background		 involves: C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Atg5em1Smoc mutation (0 available); any Atg5 mutation (29 available)
S100a4em1(cre)Zhyg mutation (0 available); any S100a4 mutation (26 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
neoplasm
abnormal tumor morphology ( J:330821 )
• reduced collagen in the pancreas of mice implanted with murine pancreatic ductal adenocarcinoma cells
decreased tumor growth/size ( J:330821 )
• due to reduced proliferation compared to when murine pancreatic ductal adenocarcinoma cells are implanted into control mice




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory