Phenotypes associated with this allele

• Allele Symbol: Ddx6^em1.2Ysa
• Allele Name: endonuclease-mediated mutation 1.2, Yumiko Saga
• Allele ID: MGI:7425331
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Ddx6^em1.2Ysa/Ddx6^em1.2Ysa	involves: C57BL/6NCrlj * CBA/JNCrlj	MGI:7425348

Genotype
MGI:7425348

hm1

• Allelic Composition: Ddx6^em1.2Ysa/Ddx6^em1.2Ysa
• Genetic Background: involves: C57BL/6NCrlj * CBA/JNCrlj

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

embryonic lethality during organogenesis, complete penetrance ( J:329565 )

• no mice are present at E11.5

embryonic lethality between implantation and placentation ( J:329565 )

• fewer than expected mice are present at E7.5

embryo

abnormal embryo development ( J:329565 )

• at E6.5

abnormal rostral-caudal axis patterning ( J:329565 )

• posterior defects at E8.5

caudal body truncation ( J:329565 )

• in some mice

embryonic growth retardation ( J:329565 )

• at E8.5

decreased embryo size ( J:329565 )

• at E7.5

abnormal primitive streak formation ( J:329565 )

• delayed formation; shortened and widened

growth/size/body

embryonic growth retardation ( J:329565 )

• at E8.5

decreased embryo size ( J:329565 )

• at E7.5