Phenotypes associated with this allele

• Allele Symbol: Ace2^{em1(IMPC)Ccpcz}
• Allele Name: endonuclease-mediated mutation 1, Institute of Molecular Genetics
• Allele ID: MGI:7425486
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Ace2^em1(IMPC)Ccpcz/Ace2^em1(IMPC)Ccpcz	C57BL/6NCrl-Ace2^em1(IMPC)Ccpcz/Ccpcz	MGI:7471849
ot2	Ace2^em1(IMPC)Ccpcz/Y	C57BL/6NCrl-Ace2^em1(IMPC)Ccpcz/Ccpcz	MGI:7471848

Genotype
MGI:7471849

hm1

• Allelic Composition: Ace2^{em1(IMPC)Ccpcz}/Ace2^{em1(IMPC)Ccpcz}
• Genetic Background: C57BL/6NCrl-Ace2^{em1(IMPC)Ccpcz}/Ccpcz

Data Sources

IMPC Data for Ace2

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

adipose tissue

increased total body fat amount ( J:211773 )

♀

IMPC - CCP-IMG

endocrine/exocrine glands

abnormal thymus morphology ( J:211773 )

♀

IMPC - CCP-IMG

enlarged thymus ( J:211773 )

♀

IMPC - CCP-IMG

growth/size/body

decreased lean body mass ( J:211773 )

♀

IMPC - CCP-IMG

enlarged spleen ( J:211773 )

♀

IMPC - CCP-IMG

hematopoietic system

abnormal thymus morphology ( J:211773 )

♀

IMPC - CCP-IMG

enlarged thymus ( J:211773 )

♀

IMPC - CCP-IMG

abnormal spleen morphology ( J:211773 )

♀

IMPC - CCP-IMG

enlarged spleen ( J:211773 )

♀

IMPC - CCP-IMG

immune system

abnormal thymus morphology ( J:211773 )

♀

IMPC - CCP-IMG

enlarged thymus ( J:211773 )

♀

IMPC - CCP-IMG

abnormal spleen morphology ( J:211773 )

♀

IMPC - CCP-IMG

enlarged spleen ( J:211773 )

♀

IMPC - CCP-IMG

reproductive system

abnormal uterus morphology ( J:211773 )

♀

IMPC - CCP-IMG

hydrometra ( J:211773 )

♀

IMPC - CCP-IMG

vision/eye

abnormal lens morphology ( J:211773 )

♀

IMPC - CCP-IMG

abnormal retina morphology ( J:211773 )

♀

IMPC - CCP-IMG

Genotype
MGI:7471848

ot2

• Allelic Composition: Ace2^{em1(IMPC)Ccpcz}/Y
• Genetic Background: C57BL/6NCrl-Ace2^{em1(IMPC)Ccpcz}/Ccpcz

Data Sources

IMPC Data for Ace2

cardiovascular system

abnormal heart morphology ( J:211773 )

♂

IMPC - CCP-IMG

enlarged heart ( J:211773 )

♂

IMPC - CCP-IMG

growth/size/body

enlarged heart ( J:211773 )

♂

IMPC - CCP-IMG

enlarged spleen ( J:211773 )

♂

IMPC - CCP-IMG

hematopoietic system

abnormal spleen morphology ( J:211773 )

♂

IMPC - CCP-IMG

enlarged spleen ( J:211773 )

♂

IMPC - CCP-IMG

immune system

abnormal spleen morphology ( J:211773 )

♂

IMPC - CCP-IMG

enlarged spleen ( J:211773 )

♂

IMPC - CCP-IMG