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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Amtem1(IMPC)Tcp
endonuclease-mediated mutation 1, The Centre for Phenogenomics
MGI:7425507
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Amtem1(IMPC)Tcp/Amtem1(IMPC)Tcp C57BL/6N-Amtem1(IMPC)Tcp/Cmmr MGI:7551038
ht2
 		Amtem1(IMPC)Tcp/Amt+ C57BL/6N-Amtem1(IMPC)Tcp/Cmmr MGI:7551037


Genotype
MGI:7551038
hm1
Allelic
Composition		 Amtem1(IMPC)Tcp/Amtem1(IMPC)Tcp
Genetic
Background		 C57BL/6N-Amtem1(IMPC)Tcp/Cmmr
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Amtem1(IMPC)Tcp mutation (1 available); any Amt mutation (31 available)
Data Sources
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
craniofacial
cleft palate ( J:211773 )
IMPC - TCP
facial cleft ( J:211773 )
IMPC - TCP

digestive/alimentary system
cleft palate ( J:211773 )
IMPC - TCP

embryo
spina bifida ( J:211773 )
IMPC - TCP

growth/size/body
abnormal facial morphology ( J:211773 )
IMPC - TCP
cleft palate ( J:211773 )
IMPC - TCP
facial cleft ( J:211773 )
IMPC - TCP
abnormal head shape ( J:211773 )
IMPC - TCP
abnormal embryo size ( J:211773 )
IMPC - TCP
abnormal abdominal wall morphology ( J:211773 )
IMPC - TCP
abnormal head size ( J:211773 )
IMPC - TCP

mortality/aging

nervous system
spina bifida ( J:211773 )
IMPC - TCP
exencephaly ( J:211773 )
IMPC - TCP

vision/eye
microphthalmia ( J:211773 )
IMPC - TCP
anophthalmia ( J:211773 )
IMPC - TCP




Genotype
MGI:7551037
ht2
Allelic
Composition		 Amtem1(IMPC)Tcp/Amt+
Genetic
Background		 C57BL/6N-Amtem1(IMPC)Tcp/Cmmr
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Amtem1(IMPC)Tcp mutation (1 available); any Amt mutation (31 available)
Data Sources
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
cardiovascular system

hematopoietic system

limbs/digits/tail
short tibia ( J:211773 )
IMPC - TCP

skeleton
short tibia ( J:211773 )
IMPC - TCP

vision/eye




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory