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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Anlnem1(IMPC)Bay
endonuclease-mediated mutation 1, Baylor College of Medicine
MGI:7425513
Summary 2 genotypes


Genotype
MGI:7551041
hm1
Allelic
Composition
Anlnem1(IMPC)Bay/Anlnem1(IMPC)Bay
Genetic
Background
C57BL/6N-Anlnem1(IMPC)Bay/BayMmucd
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Anlnem1(IMPC)Bay mutation (1 available); any Anln mutation (82 available)
Data Sources
phenotype observed in females
phenotype observed in males
N normal phenotype
mortality/aging




Genotype
MGI:7720088
hm2
Allelic
Composition
Anlnem1(IMPC)Bay/Anlnem1(IMPC)Bay
Genetic
Background
C57BL/6NJ-Anlnem1(IMPC)Bay/Mmnc
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Anlnem1(IMPC)Bay mutation (1 available); any Anln mutation (82 available)
phenotype observed in females
phenotype observed in males
N normal phenotype

Anlnem1(IMPC)Bay/Anlnem1(IMPC)Bay mice exhibit embryonic lethality, with embryos recovered at E7.5 but not at E9.5. Embryos show developmental delay and poorly organized epithelia.

mortality/aging
• homozygous embryos are present at E7.5 (11% versus expected 25%, n=27); no homozygous embryos are recovered at E9.5

embryo
• embryos show poorly organized epithelia at E7.5
• PL-1 (placental lactogen 1) signal indicates that the majority of cells recovered are trophoblast derivatives
• embryos show a developmental delay at E7.5

growth/size/body
• embryos show a developmental delay at E7.5





Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
10/22/2024
MGI 6.24
The Jackson Laboratory