Phenotypes associated with this allele

• Allele Symbol: Cst6^{em1(IMPC)Ccpcz}
• Allele Name: endonuclease-mediated mutation 1, Institute of Molecular Genetics
• Allele ID: MGI:7425617
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Cst6^em1(IMPC)Ccpcz/Cst6^em1(IMPC)Ccpcz	C57BL/6NCrl-Cst6^em1(IMPC)Ccpcz/Ccpcz	MGI:7471956
ht2	Cst6^em1(IMPC)Ccpcz/Cst6^+	C57BL/6NCrl-Cst6^em1(IMPC)Ccpcz/Ccpcz	MGI:7471955

Genotype
MGI:7471956

hm1

• Allelic Composition: Cst6^{em1(IMPC)Ccpcz}/Cst6^{em1(IMPC)Ccpcz}
• Genetic Background: C57BL/6NCrl-Cst6^{em1(IMPC)Ccpcz}/Ccpcz

Data Sources

IMPC Data for Cst6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

no spontaneous movement ( J:211773 )

IMPC - CCP-IMG

mortality/aging

preweaning lethality, complete penetrance ( J:211773 )

IMPC - CCP-IMG

Genotype
MGI:7471955

ht2

• Allelic Composition: Cst6^{em1(IMPC)Ccpcz}/Cst6⁺
• Genetic Background: C57BL/6NCrl-Cst6^{em1(IMPC)Ccpcz}/Ccpcz

Data Sources

IMPC Data for Cst6

cardiovascular system

abnormal heart morphology ( J:211773 )

♂

IMPC - CCP-IMG

enlarged heart ( J:211773 )

♂

IMPC - CCP-IMG

growth/size/body

enlarged heart ( J:211773 )

♂

IMPC - CCP-IMG

enlarged spleen ( J:211773 )

♀

IMPC - CCP-IMG

hematopoietic system

abnormal spleen morphology ( J:211773 )

IMPC - CCP-IMG

enlarged spleen ( J:211773 )

♀

IMPC - CCP-IMG

small spleen ( J:211773 )

♂

IMPC - CCP-IMG

homeostasis/metabolism

increased circulating creatine kinase level ( J:211773 )

♀

IMPC - CCP-IMG

decreased circulating serum albumin level ( J:211773 )

♀

IMPC - CCP-IMG

immune system

abnormal spleen morphology ( J:211773 )

IMPC - CCP-IMG

enlarged spleen ( J:211773 )

♀

IMPC - CCP-IMG

small spleen ( J:211773 )

♂

IMPC - CCP-IMG

integument

abnormal skin morphology ( J:211773 )

♀

IMPC - CCP-IMG

limbs/digits/tail

abnormal digit morphology ( J:211773 )

♀

IMPC - CCP-IMG

long tibia ( J:211773 )

♂

IMPC - CCP-IMG

reproductive system

abnormal uterus morphology ( J:211773 )

♀

IMPC - CCP-IMG

hydrometra ( J:211773 )

♀

IMPC - CCP-IMG

skeleton

long tibia ( J:211773 )

♂

IMPC - CCP-IMG

abnormal rib morphology ( J:211773 )

♀

IMPC - CCP-IMG

rib fusion ( J:211773 )

♀

IMPC - CCP-IMG

vision/eye

abnormal retina morphology ( J:211773 )

♀

IMPC - CCP-IMG