Phenotypes associated with this allele

• Allele Symbol: Dcaf5^{em1(IMPC)Ccpcz}
• Allele Name: endonuclease-mediated mutation 1, Institute of Molecular Genetics
• Allele ID: MGI:7425630
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Dcaf5^em1(IMPC)Ccpcz/Dcaf5^em1(IMPC)Ccpcz	C57BL/6NCrl-Dcaf5^em1(IMPC)Ccpcz/Ccpcz	MGI:7551088

Genotype
MGI:7551088

hm1

• Allelic Composition: Dcaf5^{em1(IMPC)Ccpcz}/Dcaf5^{em1(IMPC)Ccpcz}
• Genetic Background: C57BL/6NCrl-Dcaf5^{em1(IMPC)Ccpcz}/Ccpcz

Data Sources

IMPC Data for Dcaf5

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

decreased exploration in new environment ( J:211773 )

IMPC - CCP-IMG

decreased locomotor activity ( J:211773 )

♀

IMPC - CCP-IMG

hyperactivity ( J:211773 )

♂

IMPC - CCP-IMG

cardiovascular system

abnormal heart morphology ( J:211773 )

♂

IMPC - CCP-IMG

enlarged heart ( J:211773 )

♂

IMPC - CCP-IMG

craniofacial

abnormal tooth morphology ( J:211773 )

♂

IMPC - CCP-IMG

growth/size/body

enlarged heart ( J:211773 )

♂

IMPC - CCP-IMG

abnormal tooth morphology ( J:211773 )

♂

IMPC - CCP-IMG

decreased body weight ( J:211773 )

♂

IMPC - CCP-IMG

enlarged spleen ( J:211773 )

♀

IMPC - CCP-IMG

increased spleen weight ( J:211773 )

♀

IMPC - CCP-IMG

hematopoietic system

increased red blood cell distribution width ( J:211773 )

♂

IMPC - CCP-IMG

increased NK cell number ( J:211773 )

♂

IMPC - CCP-IMG

increased effector memory CD8-positive, alpha-beta T cell number ( J:211773 )

IMPC - CCP-IMG

abnormal spleen morphology ( J:211773 )

♀

IMPC - CCP-IMG

enlarged spleen ( J:211773 )

♀

IMPC - CCP-IMG

increased spleen weight ( J:211773 )

♀

IMPC - CCP-IMG

small spleen ( J:211773 )

♀

IMPC - CCP-IMG

homeostasis/metabolism

decreased circulating alkaline phosphatase level ( J:211773 )

IMPC - CCP-IMG

decreased circulating serum albumin level ( J:211773 )

IMPC - CCP-IMG

immune system

increased NK cell number ( J:211773 )

♂

IMPC - CCP-IMG

increased effector memory CD8-positive, alpha-beta T cell number ( J:211773 )

IMPC - CCP-IMG

abnormal spleen morphology ( J:211773 )

♀

IMPC - CCP-IMG

enlarged spleen ( J:211773 )

♀

IMPC - CCP-IMG

increased spleen weight ( J:211773 )

♀

IMPC - CCP-IMG

small spleen ( J:211773 )

♀

IMPC - CCP-IMG

abnormal lymph node morphology ( J:211773 )

♂

IMPC - CCP-IMG

enlarged lymph nodes ( J:211773 )

♂

IMPC - CCP-IMG

limbs/digits/tail

short tibia ( J:211773 )

IMPC - CCP-IMG

respiratory system

increased lung elastance ( J:211773 )

♀

IMPC - CCP-IMG

skeleton

abnormal tooth morphology ( J:211773 )

♂

IMPC - CCP-IMG

short tibia ( J:211773 )

IMPC - CCP-IMG

vision/eye

abnormal retina morphology ( J:211773 )

♂

IMPC - CCP-IMG