Analysis Tools|
Allele Symbol Allele Name Allele ID |
Ddx10em1(IMPC)Bay endonuclease-mediated mutation 1, Baylor College of Medicine MGI:7425631 |
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| Summary |
3 genotypes
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Data Sources
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
Ddx10em1(IMPC)Bay/Ddx10em1(IMPC)Bay mice exhibit embryonic lethality, with embryos recovered at E3.5 but not at E7.5. Embryos at E3.5 appear as dying morulae. Mutants fail to hatch from the zona pellucida and are dead after 72 outgrowth assay.
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• homozygous embryos are present in nearly normal Mendelian ratios at E3.5 and appear as dying morulae; no homozygous embryos are recovered at E7.5
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• in vitro outgrowth assays show that embryos fail to hatch from the zona pellucida and are dead after 3 days in culture
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• embryos recovered at E3.5 appear as dying morulae
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Data Sources
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
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IMPC - BCM
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IMPC - BCM
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IMPC - BCM
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IMPC - BCM
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 12/10/2024 MGI 6.24 |
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