Analysis Tools|
Allele Symbol Allele Name Allele ID |
Ddx18em1(IMPC)Bay endonuclease-mediated mutation 1, Baylor College of Medicine MGI:7425632 |
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| Summary |
3 genotypes
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Data Sources
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
Ddx18em1(IMPC)Bay/Ddx18em1(IMPC)Bay mice exhibit embryonic lethality, with embryos recovered at E3.5 as uncompacted morulae but not at E7.5. Mutants fail to hatch from the zona pellucida and are dead after 3 days in culture.
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• homozygous embryos can be recovered at E3.5 (12% versus expected 25%, n=34) and appear as uncompacted morulae; no homozygous embryos or excess resorption sites are observed at E7.5
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• in vitro, embryos fail to hatch from the zona pellucida and are dead after 3 days in culture
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• embryos recovered at E3.5 appear as uncompacted morulae
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Data Sources
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
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IMPC - BCM
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IMPC - BCM
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IMPC - BCM
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IMPC - BCM
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 11/19/2024 MGI 6.24 |
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