Phenotypes associated with this allele

• Allele Symbol: Pomk^{em1(IMPC)Hmgu}
• Allele Name: endonuclease-mediated mutation 1, Helmholtz Zentrum Muenchen GmbH
• Allele ID: MGI:7425922
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Pomk^em1(IMPC)Hmgu/Pomk^em1(IMPC)Hmgu	C57BL/6NCrl-Pomk^em1(IMPC)Hmgu/Ieg	MGI:7472179
ht2	Pomk^em1(IMPC)Hmgu/Pomk^+	C57BL/6NCrl-Pomk^em1(IMPC)Hmgu/Ieg	MGI:7472178

Genotype
MGI:7472179

hm1

• Allelic Composition: Pomk^{em1(IMPC)Hmgu}/Pomk^{em1(IMPC)Hmgu}
• Genetic Background: C57BL/6NCrl-Pomk^{em1(IMPC)Hmgu}/Ieg

Data Sources

IMPC Data for Pomk

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

preweaning lethality, complete penetrance ( J:211773 )

IMPC - HMGU

Genotype
MGI:7472178

ht2

• Allelic Composition: Pomk^{em1(IMPC)Hmgu}/Pomk⁺
• Genetic Background: C57BL/6NCrl-Pomk^{em1(IMPC)Hmgu}/Ieg

Data Sources

IMPC Data for Pomk

behavior/neurological

decreased startle reflex ( J:211773 )

IMPC - HMGU

growth/size/body

increased spleen weight ( J:211773 )

♀

IMPC - HMGU

hematopoietic system

increased spleen weight ( J:211773 )

♀

IMPC - HMGU

immune system

increased spleen weight ( J:211773 )

♀

IMPC - HMGU

renal/urinary system

abnormal kidney morphology ( J:211773 )

♂

IMPC - HMGU

skeleton

increased bone mineral density ( J:211773 )

♂

IMPC - HMGU